State police blocked off more than a five-mile section of Harmony Road, which runs right along the Susquehanna River, for a possible water rescue.
A state police spokesman would only say crews were following up on some leads.
Emergency vehicles from several of the surrounding areas were on scene.
Crews were called out around 2:30 p.m. Friday afternoon.
Officials are not saying who or what may be in the river in the Great Bend Township.
Around 7 p.m. Friday night, all crews left the area. An officer said they were wrapped up for the day.
A spokesman would not say if the first responders would be returning to the area.
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